But the only real 4-MAR/Aminorex typre drug we have seen is 4,4-Dimethylaminorex, and that was chargeable for a number of deaths. We all know from phendimetrazine that substitutions to the Nitrogen reduced the potency or must be demthylated in vitro rendering it a prodrug. Regarding intranasal/buccal/sublingual use, I am not certain if this is a